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Synthesis using Nature’s catalysts; enzymes

Stephen Bell Biocatalyst 2

Honours project: Projects in this area involve the isolation and study new enzymes from bacteria of interest or taking existing enzymes and adapting them for chemical synthesis.

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Improving food safety using plasma sterilisation

Improving food safety using plasma sterilisation

Honours project: Investigate the use of a high energy form of matter (plasma) to improve food safety.

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Mixed colony biofilms & disease outcome

Honours project: This molecular and biomedical science honours project explores mixed colony biofilms and their relationship to disease outcomes.

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Group B Strep & oxidative stress

Dr Stephen Kidd

Honours project: Identify the response of Group B Streptococcus to relevant reactive oxygen and reactive nitrogen species.

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Role of eEF2K & cancer cell migration & invasion

Cancer cells survive and gain the ability to spread under microenvironmental stress conditions through the inhibition of mTORC1 and subsequent activation of eEF2K

Honours project: Study cell signalling and gene regulation through the exploration of the role of eukaryotic elongation factor 2 kinase (eEF2K) and cancer cell migration and invasion.

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Staphylococcus aureus & lifestyle variations

Stephen Kidd Staph

Honours project: Conduct biomedical research into Staphylococcus aureus (Golden staph).

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Understanding the molecular mechanisms of intellectual disability

Honours project: Investigate the role IQSEC2 and synaptic morphology and plasticity on the orchestration of the complex architecture required for ‘normal’ cognition.

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Systematic analysis of the eIF4E interactome

Active mTORC1 phosphorylates 4E-BP, preventing 4E1 binding. (B) mTORC1 inhibition leads to 4E-BP hypophosphorylation; 4E-BP now binds 4E1 and blocks eIF4F

Honours project: Conduct a systematic analysis of the eIF4E interactome to understand the distinct functional roles of the three mammalian eIF4E proteins in translation initiation.

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Unwrapping the 3D genome to map autoimmune disease

Honours project: Help unravel the chromatin interactome to map the genetic risk of type 1 diabetes.

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Genetic mutations associated with skin & wool growth in sheep

Animal science sheep

Honours project: Identify genetic mutations in sheep DSC1 & DSG4 genes essential for skin and wool follicle architecture.

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Competition: Young Scientist of the Year

How do we feed the world’s growing population? How do we save our wildlife from extinction? Got an idea that will build a brighter, greener world?

Australian high school students are invited to submit a short video about one of Australia’s big science challenges.

Video competition