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Role of eEF2K & cancer cell migration & invasion

Cancer cells survive and gain the ability to spread under microenvironmental stress conditions through the inhibition of mTORC1 and subsequent activation of eEF2K

Honours project: Study cell signalling and gene regulation through the exploration of the role of eukaryotic elongation factor 2 kinase (eEF2K) and cancer cell migration and invasion.

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Group B Strep & oxidative stress

Dr Stephen Kidd

Honours project: Identify the response of Group B Streptococcus to relevant reactive oxygen and reactive nitrogen species.

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Mixed colony biofilms & disease outcome

Honours project: This molecular and biomedical science honours project explores mixed colony biofilms and their relationship to disease outcomes.

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Understanding the molecular mechanisms of intellectual disability

Honours project: Investigate the role IQSEC2 and synaptic morphology and plasticity on the orchestration of the complex architecture required for ‘normal’ cognition.

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Systematic analysis of the eIF4E interactome

Active mTORC1 phosphorylates 4E-BP, preventing 4E1 binding. (B) mTORC1 inhibition leads to 4E-BP hypophosphorylation; 4E-BP now binds 4E1 and blocks eIF4F

Honours project: Conduct a systematic analysis of the eIF4E interactome to understand the distinct functional roles of the three mammalian eIF4E proteins in translation initiation.

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Unwrapping the 3D genome to map autoimmune disease

Honours project: Help unravel the chromatin interactome to map the genetic risk of type 1 diabetes.

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Working with animals: Knowledge of delegated legislation in biomedical research

Lab mouse

Honours project: Undertake qualitative research methods to determine personnel awareness and knowledge of a range of secondary legislative documents pertaining to the use of animals in research.

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Do gut microbes promote migratory fattening in shorebirds?

This animal science honours projects aims to determine if gut microbes promote migratory fattening in shorebirds, using commercial broiler chickens as a model.

Honours project: Determine if gut microbes promote migratory fattening in shorebirds, using commercial broiler chickens as a model.

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Genetic mutations associated with skin & wool growth in sheep

Animal science sheep

Honours project: Identify genetic mutations in sheep DSC1 & DSG4 genes essential for skin and wool follicle architecture.

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Stockpersons' knowledge of Codes of Practice in the pig industry

Piglets at Roseworthy campus

Honours project: Undertake qualitative research methods to determine farmer awareness and knowledge of a range of secondary legislative documents pertaining to the pig industry.

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