Cat sensitivity to the insecticide permethrin

Why are cats so sensitive to the insecticide permethrin, unlike other mammals and birds?

Cat sleeping

This project aims to compare specific features of feline voltage-gated sodium channels with those of other species to determine explain feline sensitivity to permethrin.

Voltage-gated sodium channels are a major target of permethrin in insects and other species. Unlike insects, most mammals are very resistant to the effects of permethrin, but cats are easily poisoned.

Key methodology: In silico analyses of protein structure and potential function; possibly cloning and sequencing mRNA from cat central nervous system.

Anne Peaston

Supervisor

Dr Anne Peaston

Research area: Companion animal health

Recommended honours enrolment: Honours in Animal Science

Tagged in Honours projects - Animal science, Honours projects - Ecology and environmental science, Honours projects - Anne Peaston, Honours in Animal Science subtheme - Companion animal health