Can Emu Oil & Japanese Kampo medicine treat bowel cancer?

Examine the impact of Emu Oil treatment, in combination with Japanese Kampo medicine, on mouse behaviour in a model of colitis-associated colorectal cancer.

This project seeks to determine behavioural modifications resulting from combined Emu Oil and Kampo treatment in a mouse model of colitis-associated colorectal cancer. 

Ulcerative colitis, a type of inflammatory bowel disease, is a lifelong condition characterised by unremitting inflammation of the distal bowel. Persistent inflammation causes cells to grow uncontrollably, resulting in colorectal cancer.

Previously, we demonstrated the anti-inflammatory and reparative properties of orally-administered Emu Oil in animal models of intestinal disease.

The impact of a combined therapy of Emu Oil with Kampo medicine (a traditional Japanese herbal medicine) on mouse behaviour is yet to be investigated.

Key methodology: You will co-run a 9-week mouse study assessing different aspects of behaviour including burrowing, nesting and facial grimace of mice.

Suzanne Mashtoub

Supervisors

Dr Suzanne Mashtoub

Co-supervisors: Dr Alexandra Whittaker | Professor Gordon Howarth

Research area: Pathobiology, infectious disease & public health

Recommended honours enrolment: Honours in Animal Science

Tagged in Honours projects - Animal science, Honours projects - Molecular and biomedical science, Honours in Animal Science subtheme - Pathobiology infectious disease and public health, Honours projects - Suzanne Mashtoub, Honours projects - Gordon Howarth, Honours projects - Alexandra Whittaker, Honours projects - Molecular and biomedical science: Other