Do MPS patient derived stem cells form bone and cartilage?
This project in genetics and molecular pathology examines the characterisation of patient derived stem cells.
Children with the genetic disease mucopolysaccharidosis (MPS) have a range of symptoms including progressive, severe skeletal pathology that manifests as low bone mass and extreme short stature.
We have generated mesenchymal stem cells from patient-derived iPSCs and will use these stem cells to determine how different mutations affect bone and cartilage formation and function. The goal is to understand how pathology arises in the skeleton.
The Matrix Biology Unit is located at the Womens and Children’s Hospital, North Adelaide.
Whether you're still at high school or planning to join us mid-year, taking a break from study or rethinking your career path, come chat with us at our STEM Careers Night.
You and your parents are invited to join us on campus on Tuesday 18 May to see what’s available in the world of STEM.