Honours information session

Thursday May 6 2.30pm

Join us for a short online session to discover why honours could be the right choice for you.

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Determining the effect of protein quality control to astrocyte stress responses

Determining the effect of protein quality control to astrocyte stress responses

This honours project aims to determine the effect of protein quality control to astrocyte stress responses.

Proteostasis, the homeostasis of protein folding and degradation, is an essential regulator of cell function. We have identified a subset of proteins important for disposing and recognising misfolded proteins in cells through a process called protein quality control. 

We are interested in how brain cells are adapting to different stress responses, and what happens to this adaptation if the protein quality control is compromised.

Astrocytes are the main glial cell type in central nervous system that is responsible for support and maintenance. 

This current scientific project will use cultured astrocytes to determine how malfunction in our identified factors will effect on astrocyte reactive gene and protein expression during oxidative stress and in Parkinson’s disease. 

The project will use cell culture, some amount of biochemical and cell biological assays especially qPCR suitable for students with a background in molecular and biomedical sciences.

This project is based at the South Australian Health and Medical Research Institute (SAHMRI).


 

Pirjo Apaja

Supervisor

Associate Professor Pirjo Apaja

Research area: Molecular and biomedical sciences, Apaja Group

Recommended honours enrolment: Honours in Molecular and Biomedical Science

Tagged in Honours projects - Molecular and biomedical science, Honours projects - Molecular and biomedical science: Biochemistry, Honours projects - Pirjo Apaja

STEM Careers Night: On-campus and online

Whether you're still at high school or planning to join us mid-year, taking a break from study or rethinking your career path, come chat with us at our STEM Careers Night.

You and your parents are invited to join us on campus on Tuesday 18 May to see what’s available in the world of STEM.

STEM Careers Night