Ubiquitin signalling in human diseases
This honours project will investigate the effect of ubiquitin signalling on cell differentiation.
The ubiquitin signalling regulates cell differentiation, protein degradation and membrane trafficking. This project will investigate the subset of identified deubiquitinating enzymes and will determine their modulator effect on dopaminergic neuronal differentiation and signalling in different conditions.
You will express and deplete the enzyme targets for functional analyses.
This exciting project is based at the South Australian Health and Medical Research Institute (SAHMRI).
You will use human proteins associated with cancers, neurodevelopment and neurodegenerative diseases. The project will use range of biochemical and cell and molecular biological assays and cell culture suitable for students from molecular and biomedical sciences.
Whether you're still at high school or planning to join us mid-year, taking a break from study or rethinking your career path, come chat with us at our STEM Careers Night.
You and your parents are invited to join us on campus on Tuesday 18 May to see what’s available in the world of STEM.