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Cell division & cancer

Honours project: Explore the molecular machinery that controls cell division to allow rational cancer chemotherapy.

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Deciphering the catalytic potential & the electron transfer pathways of microorganisms

Electron transfer pathways

Honours project: Study new enzymes and the associated ferredoxins from bacteria found in interesting environments (or genes from metagenomes) or which carry out novel reactions.

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Synthetic biology applications of enzymes

Honours project: Use approaches to generate enzyme catalyst based systems to develop greener and sustainable processes for the production of useful and high value chemicals.

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Understanding the mechanism of enzyme catalysed reactions of importance in drug metabolism

Stephen Bell - Mechanism of enzyme catalysed reactions of importance in drug metabolism

Honours project: Learn about the mechanism by which the major family of enzymes involved in drug metabolism catalyse oxidative transformations.

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Synthesis using Nature’s catalysts; enzymes

Stephen Bell Biocatalyst 2

Honours project: Projects in this area involve the isolation and study new enzymes from bacteria of interest or taking existing enzymes and adapting them for chemical synthesis.

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Group B Strep & oxidative stress

Dr Stephen Kidd

Honours project: Identify the response of Group B Streptococcus to relevant reactive oxygen and reactive nitrogen species.

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Mixed colony biofilms & disease outcome

Honours project: This molecular and biomedical science honours project explores mixed colony biofilms and their relationship to disease outcomes.

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Staphylococcus aureus & lifestyle variations

Stephen Kidd Staph

Honours project: Conduct biomedical research into Staphylococcus aureus (Golden staph).

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Role of eEF2K & cancer cell migration & invasion

Cancer cells survive and gain the ability to spread under microenvironmental stress conditions through the inhibition of mTORC1 and subsequent activation of eEF2K

Honours project: Study cell signalling and gene regulation through the exploration of the role of eukaryotic elongation factor 2 kinase (eEF2K) and cancer cell migration and invasion.

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Unwrapping the 3D genome to map autoimmune disease

Honours project: Help unravel the chromatin interactome to map the genetic risk of type 1 diabetes.

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